Select two disorders of the male and/or female reproductive systems that interest you. Consider the similarities and differences between the disorders.

NURS6521 week 11 Discussion: Off-Label Drug Use in Pediatrics

The unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable since very few drugs have been specifically researched and tested with children.

When treating children, prescribers often adjust dosages approved for adults to accommodate a child’s weight. However, children are not just “smaller” adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism, and excretion. Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group.

To prepare:

Review the Bazzano et al. and Mayhew articles in the Learning Resources. Reflect on situations in which children should be prescribed drugs for off-label use.
Think about strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Consider specific off-label drugs that you think require extra care and attention when used in pediatrics.
With these thoughts in mind:

By Day 3

Post an explanation of circumstances under which children should be prescribed drugs for off-label use. Then, describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.

By Day 6

Read a selection of your colleagues’ responses and respond to at least two of your colleagues on two different days who provided a different rationale than you did, in one or more of the following ways:

Offer and support an alternative perspective using readings from the classroom or from your own research in the Walden Library.
Validate an idea with your own experience and additional research.
NURS6501 week 11 Discussion: Disorders of the Reproductive Systems

While the male and female reproductive systems are unique to each sex, they share a common function—reproduction. Disorders of this system range from delayed development to structural and functional abnormalities. Since many reproductive disorders not only result in physiological consequences but also psychological consequences such as embarrassment, guilt, or profound disappointment, patients are often hesitant to seek treatment. Advanced practice nurses need to educate patients on disorders and help relieve associated stigmas. During patient evaluations, patients must feel comfortable answering questions so that you, as a key health care provider, will be able to diagnose and recommend treatment options. As you begin this Discussion, consider reproductive disorders that you would commonly see in the clinical setting.

To Prepare

Review Chapter 22 and Chapter 23 in the McPhee and Hammer text, as well as Chapter 32 in the Huether and McCance text.
Select two disorders of the male and/or female reproductive systems that interest you. Consider the similarities and differences between the disorders.
Select one of the following factors: genetics, ethnicity, age, or behavior. Think about how the factor you selected might impact the diagnosis of and treatment for the reproductive disorders.
By Day 3

Post a description of the two reproductive disorders you selected, including their similarities and differences. Then explain how the factor you selected might impact the diagnosis of treatment for the reproductive disorders.

Read a selection of your colleagues’ responses.

By Day 6

Respond to at least two of your colleagues on two different days who selected different disorders or factors than you, in one or more of the following ways:

Share insights on how the factor you selected impacts the pathophysiology of the disorder your colleague selected.
Offer alternative diagnoses and prescription of treatment options for the disorder your colleague selected.
Validate an idea with your own experience and additional research.

Can human experimentation be justified when the greater good of society is at stake?

200 words 2 references within 5 years (prefer nursing journals or peer reviewed only)

Henrietta Lackswas an African American woman whose cancer cells were the source of the HeLa cell line, one of the most important cell lines in medical research. HeLa cells are “immortalized cells.” Immortalized cells lines are important because they will reproduce indefinitely under specific conditions. The HeLa immortal cell line was vital for creating the polio vaccine, cloning (i.e., Dolly the sheep), gene mapping (i.e., the Human Genome Project) and more.

Mrs. Lacks was the unwitting source of these cells when her tumor was biopsied in 1951 during treatment for cervical cancer at Johns Hopkins Hospital in Maryland. Her cells were then cultured by George Otto Gey, who created the cell line known as “HeLa” (i.e., Henrietta Lacks). Consent was NOT obtained to culture her cells, nor was she (or her family) ever compensated for the use of the cells despite the fact that the HeLa cell line revolutionized modern medicine!

As we examine ethics for nursing research and evidence-based practice, please consider and present examples of human experimentation that have occurred during the history of medical research. Have these projects resulted in beneficial outcomes for society? Can human experimentation be justified when the greater good of society is at stake?

How can you apply transformation leadership into nursing management and change the attitudes of the staff and encourage a more cohesive team atmosphere?

APA Format 1000+ words

Evidence based practice: Please use a minimum of 3 references (Research articles preferred or journals) (Can’t be textbook or websites)

How can you apply transformation leadership into nursing management and change the attitudes of the staff and encourage a more cohesive team atmosphere?

What effects would this leadership style have on management and how will affect retention of the work force in a healthcare setting (Nursing Specific)?

How this style of management when providing transformational leadership usually applies in nursing?